How is chronic pain related to sympathetic dysfunction and autonomic dysreflexia following spinal cord injury?
نویسندگان
چکیده
منابع مشابه
Autonomic dysreflexia: a cardiovascular disorder following spinal cord injury
Autonomic dysreflexia (AD) is a serious cardiovascular disorder in patients with spinal cord injury (SCI). The primary underlying cause of AD is loss of supraspinal control over sympathetic preganglionic neurons (SPNs) caudal to the injury, which renders the SPNs hyper-responsive to stimulation. Central maladaptive plasticity, including C-fiber sprouting and propriospinal fiber proliferation ex...
متن کاملRegional sympathetic function in high spinal cord injury during mental stress and autonomic dysreflexia.
Centrally mediated sympathetic stimulation of subjects who have suffered a spinal cord injury (SCI) does not activate the decentralized part of the body below the level of the lesion, whereas experimental data indicate an exaggerated response above the level of the lesion. SCI subjects may exhibit an autonomic dysreflexia reaction following afferent stimulation below the level of the lesion. In...
متن کاملAcute Severe Autonomic Dysreflexia during Spinal Cord Intramedullary Tumor Resectione
Background & Importance: Acute autonomic system impairment can be dangerous and life-threatening, and a clinician should be aware of its occurrence possibility. According to the anatomy of this system, spinal cord lesions could disturb its function. There are many reports of autonomic dysreflexia in spinal cord i njuries especially spinal cord trauma. Case Presentation: A 28 year-o...
متن کاملCardiac Consequences of Autonomic Dysreflexia in Spinal Cord Injury.
Autonomic dysreflexia (AD), which describes episodic hypertension, is highly prevalent in people with spinal cord injury (SCI). In non-SCI, primary hypertension depresses cardiac contractile reserve via β-adrenergic mechanisms. In this study, we investigated whether AD contributes to the impairment in cardiac contractile function that accompanies SCI. We induced SCI in rodents and stratified th...
متن کاملAutonomic dysreflexia in a parturient with spinal cord injury.
Autonomic dysreflexia (ADR) is a syndrome of imbalanced reflex sympathetic discharge occurring in patients with spinal cord injury (SCI) at or above the level of splanchnic sympathetic outflow (T6). We present the case of a 29 year-old, gravida 3, para 1 Caucasian female at 28 weeks gestation, with a history of T3 SCI secondary to a gunshot wound 9 years prior, who developed ADR during preterm ...
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ژورنال
عنوان ژورنال: Autonomic Neuroscience
سال: 2018
ISSN: 1566-0702
DOI: 10.1016/j.autneu.2017.01.006